Selected Publications
Our team has a strong publication record, with research published in leading journals, including Nature Medicine, Nature Genetics and Cell Genomics. Below are some selected publications.
- Fatumo S, Ojewunmi O, Camenzuli R, Kintu C, Kamiza A, Brandenburg JT, Kalungi A, Kalyesubula R, Salako B, Nash O, Crampin A. KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease. Nature Genetics. 2025 Sep;57(9):2079-82.
- Corpas M, Guio H, Lopez-Correa C, Fatumo S. Why genomic diversity should not be framed by census alone. Nature Genetics. 2025 Jul 29:1-2.
- Corpas M, Pius M, Poburennaya M, Guio H, Dwek M, Nagaraj S, Lopez-Correa C, Popejoy A, Fatumo S. Bridging genomics’ greatest challenge: The diversity gap. Cell genomics. 2025 Jan 8;5(1).
- Ojewunmi OO, Fatumo S. Driving Global Health equity and precision medicine through African genomic data. Human Molecular Genetics. 2025 Apr 30:ddaf025.
- Smit RA, Wade KH, Hui Q, Arias JD, Yin X, Christiansen MR, Yengo L, Preuss MH, Nakabuye M, Rocheleau G, Graham SE....Fatumo, S,. Polygenic prediction of body mass index and obesity through the life course and across ancestries. Nature medicine. 2025 Sep;31(9):3151-68.
- Katte JC, Squires S, Dehayem MY, Balungi PA, Padoa CJ, Sengupta D, Fatumo S, Piloya T, Nyangabyaki-Twesigye C, Bahendeka S, Majaliwa E. Non-autoimmune, insulin-deficient diabetes in children and young adults in Africa: evidence from the Young-Onset Diabetes in sub-Saharan Africa (YODA) cross-sectional study. The Lancet Diabetes & Endocrinology. 2025 Sep 1;13(9):745-53.
- Williamson, A., & Fatumo, S. Genomic diversity improves disease discovery for all. Science, 385(6706), 255-256.
- Kalungi A, Stein DJ, Okewole N, Fatumo S. Approaches to enable equitable psychiatric genetic research in Africa. Communications medicine. 2024 Oct 25;4(1):216.
- Mentzer AJ, Dilthey AT, Pollard M, Gurdasani D, Karakoc E, Carstensen T, Muhwezi A, Cutland C, Diarra A, da Silva Antunes R, Paul S. High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response. Nature Medicine. 2024 May;30(5):1384-94.
- Fatumo S. Including diverse populations enhances the discovery of type 2 diabetes loci. Nature Reviews Genetics. 2024 Feb;25(2):82-.
- Kalungi, A., Kinyanda, E., Akena, D. H., Gelaye, B., Ssembajjwe, W., Mpango, R. S., ... & Fatumo, S. (2024). Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research. Molecular psychiatry, 1-9.
- Soremekun, O., Mhlongwe, T., Kirabo, G., Akinyele, C., Chikowore, T., Fatumo, S., & Gill, D. (2024). Genetically Proxied Lipid-Lowering Drug Target Perturbation and Ischemic Stroke Risk in European and African Ancestry Individuals: Mendelian Randomization Study. Stroke.
- Katrinli S, Wani AH, Maihofer AX, Ratanatharathorn A, Daskalakis NP, Montalvo-Ortiz J, Núñez-Ríos DL, Zannas AS, Zhao X, Aiello AE, Ashley-Koch AE. Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts. Genome medicine. 2024 Dec 18;16(1):147.
- Wang S, Ojewunmi OO, Kamiza A, Ramsay M, Morris AP, Chikowore T, Fatumo S, Asimit JL. Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies. Communications Biology. 2024 Nov 14;7(1):1512.
- Kullo, I. J., Conomos, M. P., Nelson, S. C., Adebamowo, S. N., Choudhury, A., Conti, D., ...S Fatumo et al & Wiley, L. (2024). The PRIMED Consortium: Reducing disparities in polygenic risk assessment. The American Journal of Human Genetics, 111(12), 2594-2606.
- Kamiza AB, Touré SM, Zhou F, Soremekun O, Cissé C, Wélé M, Touré AM, Nashiru O, Corpas M, Nyirenda M, Crampin A. Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry. Nature Communications. 2023 Sep 5;14(1):5403.
- Fatumo, S., & Choudhury, A. (2023). African American genomes don't capture Africa's genetic diversity. Nature, 617(7959), 35-35.
- McLaren PJ, Porreca I, Iaconis G, Mok HP, Mukhopadhyay S, Karakoc E, Cristinelli S, Pomilla C, Bartha I, Thorball CW, Tough RH.... Fatumo, S Africa-specific human genetic variation near CHD1L associates with HIV-1 load. Nature. 2023 Aug 31;620(7976):1025-30.
- Fatumo S, Sathan D, Samtal C, Isewon I, Tamuhla T, Soremekun C, Jafali J, Panji S, Tiffin N, Fakim YJ. Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions. Genome Medicine. 2023 Oct 30;15(1):87.
- Fatumo, S., & Inouye, M. (2023). African genomes hold the key to accurate genetic risk prediction. Nature Human Behaviour, 7(3), 295-296
- Mayanja R, Machipisa T, Soremekun O, Kamiza AB, Kintu C, Kalungi A, Kalyesubula R, Sande OJ, Jjingo D, Fabian J, Robinson-Cohen C. Genome-wide association analysis of cystatin-C kidney function in continental Africa. EBioMedicine. 2023 Sep 1;95.
- Soremekun, O., Musanabaganwa, C., Uwineza, A., Ardissino, M., Rajasundaram, S., Wani, A. H., ... & Fatumo, S. (2023). A Mendelian randomization study of genetic liability to post-traumatic stress disorder and risk of ischemic stroke. Translational Psychiatry, 13(1), 237.
- Kintu C, Soremekun O, Kamiza AB, Kalungi A, Mayanja R, Kalyesubula R, Bagaya B, Jjingo D, Fabian J, Gill D, Nyirenda M. The causal effects of lipid traits on kidney function in Africans: bidirectional and multivariable Mendelian-randomization study. EBioMedicine. 2023 Apr 1;90.
- Kamiza AB, Toure SM, Vujkovic M, Machipisa T, Soremekun OS, Kintu C, Corpas M, Pirie F, Young E, Gill D, Sandhu MS. Transferability of genetic risk scores in African populations. Nature Medicine. 2022 Jun;28(6):1163-6.
- Chikowore, T., Ekoru, K., Vujkovi, M., Gill, D., Pirie, F., Young, E., ... & Fatumo, S. (2022). Polygenic prediction of type 2 diabetes in Africa. Diabetes care, 45(3), 717-723.
- Fatumo S, Chikowore T, Choudhury A, Ayub M, Martin AR, Kuchenbaecker K. A roadmap to increase diversity in genomic studies. Nature medicine. 2022 Feb;28(2):243-50.
- Fatumo S, Yakubu A, Oyedele O, Popoola J, Attipoe DA, Eze-Echesi G, Modibbo FZ, Ado-Wanka N, Salako O. Promoting the genomic revolution in Africa through the Nigerian 100K Genome Project. Nature Genetics. 2022 May;54(5):531-6.
- Fatumo S, Mugisha J, Soremekun OS, Kalungi A, Mayanja R, Kintu C, Makanga R, Kakande A, Abaasa A, Asiki G, Kalyesubula R. Uganda Genome Resource: a rich research database for genomic studies of communicable and non-communicable diseases in Africa. Cell Genomics. 2022 Nov 9;2(11).
- Adebamowo CA, Adeyemo A, Ashaye A, Akpa OM, Chikowore T, Choudhury A, Fakim YJ, Fatumo S, Hanchard N, Hauser M, Mitchell B. Polygenic risk scores for CARDINAL study. Nature genetics. 2022 May;54(5):527-30.
- Soremekun O, Karhunen V, He Y, Rajasundaram S, Liu B, Gkatzionis A, Soremekun C, Udosen B, Musa H, Silva S, Kintu C. Lipid traits and type 2 diabetes risk in African ancestry individuals: a Mendelian randomization study. EBioMedicine. 2022 Apr 1;78.
- Zhou W, Kanai M, Wu KH, Rasheed H, Tsuo K, Hirbo JB, Wang Y, Bhattacharya A, Zhao H, Namba S, Surakka I, Fatumo S. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. Cell genomics. 2022 Oct 12;2(10).
- Udosen B, Soremekun O, Ekenna C, Idowu Omotuyi O, Chikowore T, Nashiru O, Fatumo S. In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure. BMC research notes. 2021 Dec 20;14(1):457.
- Soremekun O, Soremekun C, Machipisa T, Soliman M, Nashiru O, Chikowore T, Fatumo S. Genome-wide association and Mendelian randomization analysis reveal the causal relationship between white blood cell subtypes and asthma in Africans. Frontiers in genetics. 2021 Dec 2;12:749415.
- Babah OA, Ojewunmi OO, Osuntoki AA, Simon MA, Afolabi BB. Genetic polymorphisms of Vascular Endothelial Growth Factor (VEGF) associated with endometriosis in Nigerian women. Human genomics. 2021 Oct 30;15(1):64.
- Machipisa T, Chong M, Muhamed B, Chishala C, Shaboodien G, Pandie S, de Vries J, Laing N, Joachim A, Daniels R, Ntsekhe M. Association of novel locus with rheumatic heart disease in Black African individuals: findings from the RHDGen study. JAMA cardiology. 2021 Sep 1;6(9):1000-11.
- Adekunle MO, Ojewunmi O, Animasahun AB, Lawani FO, Ubuane PO. Prevalence, determinants and impact of haemoglobin phenotype misdiagnosis among parents of children living with sickle cell disease in Nigeria. The Journal of Pediatric Research. 2021 Aug 20.
- Fatumo S, Karhunen V, Chikowore T, Sounkou T, Udosen B, Ezenwa C, Nakabuye M, Soremekun O, Daghlas I, Ryan DK, Taylor A. Metabolic traits and stroke risk in individuals of African ancestry: Mendelian randomization analysis. Stroke. 2021 Aug;52(8):2680-4.
- Adeyemo TA, Ojewunmi OO, Oyetunji IA, Kalejaiye OO, Menzel S. Fetal‐haemoglobin enhancing genotype at BCL11A reduces HbA2 levels in patients with sickle cell anaemia. EJHaem. 2021 Aug;2(3):459-61.
- Ojewunmi OO, Adeyemo TA, Oyetunji AI, Benn Y, Ekpo MG, Iwalokun BA. Association of alpha‐thalassemia and Glucose‐6‐Phosphate Dehydrogenase deficiency with transcranial Doppler ultrasonography in Nigerian children with sickle cell anemia. Journal of clinical laboratory analysis. 2021 Jun;35(6):e23802.
- Chikowore T, Kamiza AB, Oduaran OH, Machipisa T, Fatumo S. Non-communicable diseases pandemic and precision medicine: Is Africa ready?. EBioMedicine. 2021 Mar 1;65.
- Soremekun OS, Ezenwa C, Soliman M, Chikowore T, Nashiru O, Fatumo S. Transcription-translation error: In-silico investigation of the structural and functional impact of deleterious single nucleotide polymorphisms in GULP1 gene. Informatics in medicine unlocked. 2021 Jan 1;22:100503.